Normal and Sjogren’s syndrome models of the murine lacrimal gland studied at single-cell resolution
Rattner A, Heng JS, Winer BL, Goff LA, Nathans J. Normal and Sjogren's syndrome models of the murine lacrimal gland studied at single-cell resolution. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2311983120. doi: 10.1073/pnas.2311983120. Epub 2023 Oct 9. PMID: 37812717; PMCID: PMC10589653. Link
Signaling Pathways in Neurovascular Development
Rattner A, Wang Y, Nathans J. Signaling Pathways in Neurovascular Development. Annu Rev Neurosci. 2022 Jul 8;45:87-108. doi: 10.1146/annurev-neuro-111020-102127. PMID: 35803586. Link
Bacterial meningitis in the early postnatal mouse studied at single-cell resolution
Wang J, Rattner A, Nathans J. Bacterial meningitis in the early postnatal mouse studied at single-cell resolution. Elife. 2023 Jun 15;12:e86130. doi: 10.7554/eLife.86130. PMID: 37318981; PMCID: PMC10270687. Link
Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus
Rattner A, Terrillion CE, Jou C, Kleven T, Hu SF, Williams J, Hou Z, Aggarwal M, Mori S, Shin G, Goff LA, Witter MP, Pletnikov M, Fenton AA, Nathans J. (2020) Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. Elife. 9:e62766. doi: 10.7554/eLife.62766.PMID: 33084572 [link]
Roles of HIFs and VEGF in angiogenesis in the retina and brain
Rattner A., Williams J., Nathans J. (2019) Roles of HIFs and VEGF in angiogenesis in the retina and brain. The Journal of Clinical Investigation 129 (9):3807-3820. [ link ][ pdf ]
Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures
Wang, Y, Sabbagh, MF, Gu, X, Rattner, A, Williams, J, and Nathans, J. (2019) Beta-catenin signaling regu lates barrier-specific gene expression in circumventricular organ and ocular vasculatures. eLife 8: e43257. [ pdf ]
Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution
Heng, J.S., Rattner, A., Stein-O’Brien, G.L., Winer, B.L., Jones, B.W., Vernon, H.J., Goff, L.A., and Nathans, J . (2019) Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution. Proceedings of the National Academy of Sciences USA 116:9103-9114. [ pdf ]
Affinity capture of polyribosomes followed by RNAseq (ACAPseq), a discovery platform for protein-protein interactions
Peng, X., Emiliani, F., Smallwood, P.M., Rattner, A., Lei, H., Sabbagh, M.F., and Nathans, J. (2018) Affinity capture of polyribosomes followed by RNAseq (ACAPseq), a discovery platform for protein-protein interactions. eLife 7: e40982. [ pdf ]
Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells
Sabbagh, M.F., Heng, J.S., Luo, C., Castanon, R.G., Nery, J.R., Rattner, A., Goff, L.A., Ecker, J.R., Nathans, J. (2018) Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. eLife 7: e36187 [ pdf ]
Frizzled receptors in development and disease
Wang, Y., Chang, H., Rattner, A., and Nathans, J. (2016) Frizzled receptors in development and disease. Current Topics in Developmental Biology 117: 113-139. [ pdf ]
Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling
Wang, Y., Williams, J., Rattner, A., Wu, S., Bassuk, A.G., Goffinet, A.M., and Nathans, J. (2016) Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling. Developmental Biology 419: 298-310. [ pdf ]
